Aren't you glad you asked?!?

Thank you for ASSking... the booty-bombs are a success.
Mostly.

The compound pharmacy has not made this particular antibiotic (Zithromax) into a suppository before, so I don't know if there's some tweaking that needs to happen, or if some minor discomfort is to be expected.

Jaysen will take the suppos willingly enough, but after a few seconds, he becomes concerned, and tells me it's hurting him. I told him to let me check, and he recanted, saying he was only joking. Only joking? Then why does your face look like your intestines are coming alive and threatening to take over your physical body?

I told him that he has to be honest and tell me if it hurts. He didn't. Of course. Martyr.
See, now that he's found something that he can tolerate, he's afraid that if he is deemed "not able to take it", his only other option will be oral medication again. Which he cannot tolerate. At all.

What he does do, is- take a hefty poop just before bed. We go to his room, and after the suppository is in, he lays in bed stiff as a board. After a few minutes, he'll come out of his room and ask me if his butt-medicine is melted yet. I'll tell him not yet, but in another 20 minutes it will be. He comes out 5 minutes later. Melted yet? No. 5 minutes later. Now? No.

I can see the discomfort on his face growing. I give in and tell him his time's up and the medicine is melted. He sighs relief and heads straight for the bathroom. He poos. Again. This time, there is poo and suppos in the toilet. Poo'pos. I wonder how much of the med was absorbed.

This has been our nightly routine.
He seems to be getting better anyway, and I'm just taking this first experience with antibiotic suppositories as a learning experience. We're learning how his body reacts to this new way of medicating, and we'll make adjustments as necessary for the next time.

All in all, I would still say... HUGE SUCCESS!
Time for the crappy dance. I mean happy dance.